Software accompaniment to
Yufeng Wu, Association Mapping
of Complex Diseases with Ancestral Recombination Graphs: Models and
Efficient Algorithms, in Proceedings of RECOMB 2007, pages 488-502.
TMARG is a program that takes SNP population haplotypes and
case/control phenotypes to identify disease associated sites. TMARG
takes the approach of inferring genealogical history (in the form of
ancestral recombination graph or ARG) and then using the ARGs to map
the trait. See the above figure for an example. See my paper for more
Note: Files can be downloaded using "Save
Link/Target As..." After downloading the softwares, you may
need to change file access permissions (e.g. chmod u+x TMARG). Source
code is available upon request.